Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB

Non-coding RNAs are much more common than previously thought. However, for the vast majority of non-coding RNAs, the cellular function remains enigmatic. The two long non-coding RNA (lncRNA) genes DLEU1 and DLEU2 map to a critical region at chromosomal band 13q14.3 that is recurrently deleted in sol...

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Detalles Bibliográficos
Autores principales: Garding, Angela, Bhattacharya, Nupur, Claus, Rainer, Ruppel, Melanie, Tschuch, Cordula, Filarsky, Katharina, Idler, Irina, Zucknick, Manuela, Caudron-Herger, Maïwen, Oakes, Christopher, Fleig, Verena, Keklikoglou, Ioanna, Allegra, Danilo, Serra, Leticia, Thakurela, Sudhir, Tiwari, Vijay, Weichenhan, Dieter, Benner, Axel, Radlwimmer, Bernhard, Zentgraf, Hanswalter, Wiemann, Stefan, Rippe, Karsten, Plass, Christoph, Döhner, Hartmut, Lichter, Peter, Stilgenbauer, Stephan, Mertens, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616974/
https://www.ncbi.nlm.nih.gov/pubmed/23593011
http://dx.doi.org/10.1371/journal.pgen.1003373

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