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Cell stress molecules in the skeletal muscle of GNE myopathy

BACKGROUND: Mutations of the UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine-kinase (GNE)-gene are causally related to GNE myopathy. Yet, underlying pathomechanisms of muscle fibre damage have remained elusive. In sporadic inclusion body myositis (sIBM), the pro-inflammatory cell-stress medi...

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Detalles Bibliográficos
Autores principales:	Fischer, Charlotte, Kleinschnitz, Konstanze, Wrede, Arne, Muth, Ingrid, Kruse, Niels, Nishino, Ichizo, Schmidt, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616993/ https://www.ncbi.nlm.nih.gov/pubmed/23496965 http://dx.doi.org/10.1186/1471-2377-13-24

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