Cargando…
Brain Inositol Is a Novel Stimulator for Promoting Cryptococcus Penetration of the Blood-Brain Barrier
Cryptococcus neoformans is the most common cause of fungal meningitis, with high mortality and morbidity. The reason for the frequent occurrence of Cryptococcus infection in the central nervous system (CNS) is poorly understood. The facts that human and animal brains contain abundant inositol and th...
Autores principales: | Liu, Tong-Bao, Kim, Jong-Chul, Wang, Yina, Toffaletti, Dena L., Eugenin, Eliseo, Perfect, John R., Kim, Kee Jun, Xue, Chaoyang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617100/ https://www.ncbi.nlm.nih.gov/pubmed/23592982 http://dx.doi.org/10.1371/journal.ppat.1003247 |
Ejemplares similares
-
Cryptococcus inositol utilization modulates the host protective immune response during brain infection
por: Liu, Tong-Bao, et al.
Publicado: (2014) -
Inositol Metabolism Regulates Capsule Structure and Virulence in the Human Pathogen Cryptococcus neoformans
por: Wang, Yina, et al.
Publicado: (2021) -
Transcriptional Profiles Elucidate Differential Host Responses to Infection with Cryptococcus neoformans and Cryptococcus gattii
por: Holcomb, Zachary E., et al.
Publicado: (2022) -
Cryptococcus and Beyond—Inositol Utilization and Its Implications for the Emergence of Fungal Virulence
por: Xue, Chaoyang
Publicado: (2012) -
Cryptococcus neoformans Requires a Functional Glycolytic Pathway for Disease but Not Persistence in the Host
por: Price, Michael S., et al.
Publicado: (2011)