Cargando…
Drug Target Prediction and Repositioning Using an Integrated Network-Based Approach
The discovery of novel drug targets is a significant challenge in drug development. Although the human genome comprises approximately 30,000 genes, proteins encoded by fewer than 400 are used as drug targets in the treatment of diseases. Therefore, novel drug targets are extremely valuable as the so...
Autores principales: | Emig, Dorothea, Ivliev, Alexander, Pustovalova, Olga, Lancashire, Lee, Bureeva, Svetlana, Nikolsky, Yuri, Bessarabova, Marina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617101/ https://www.ncbi.nlm.nih.gov/pubmed/23593264 http://dx.doi.org/10.1371/journal.pone.0060618 |
Ejemplares similares
-
Drug Repositioning through Systematic Mining of Gene Coexpression Networks in Cancer
por: Ivliev, Alexander E., et al.
Publicado: (2016) -
An Integrated Map of HIV-Human Protein Complexes that Facilitate Viral Infection
por: Emig-Agius, Dorothea, et al.
Publicado: (2014) -
Development of a Drug-Response Modeling Framework to Identify Cell Line Derived Translational Biomarkers That Can Predict Treatment Outcome to Erlotinib or Sorafenib
por: Li, Bin, et al.
Publicado: (2015) -
Knowledge-based analysis of proteomics data
por: Bessarabova, Marina, et al.
Publicado: (2012) -
Reconstitution of the ERG Gene Expression Network Reveals New Biomarkers and Therapeutic Targets in ERG Positive Prostate Tumors
por: Dubovenko, Alexey, et al.
Publicado: (2015)