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Detergent Screening and Purification of the Human Liver ABC Transporters BSEP (ABCB11) and MDR3 (ABCB4) Expressed in the Yeast Pichia pastoris

The human liver ATP-binding cassette (ABC) transporters bile salt export pump (BSEP/ABCB11) and the multidrug resistance protein 3 (MDR3/ABCB4) fulfill the translocation of bile salts and phosphatidylcholine across the apical membrane of hepatocytes. In concert with ABCG5/G8, these two transporters...

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Detalles Bibliográficos
Autores principales:	Ellinger, Philipp, Kluth, Marianne, Stindt, Jan, Smits, Sander H. J., Schmitt, Lutz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617136/ https://www.ncbi.nlm.nih.gov/pubmed/23593265 http://dx.doi.org/10.1371/journal.pone.0060620

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