Cargando…

Genetic Variants in the Folate Pathway and the Risk of Neural Tube Defects: A Meta-Analysis of the Published Literature

BACKGROUND: Neural Tube Defects (NTDs) are among the most prevalent and most severe congenital malformations worldwide. Polymorphisms in key genes involving the folate pathway have been reported to be associated with the risk of NTDs. However, the results from these published studies are conflicting...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ti, Lou, Jiao, Zhong, Rong, Wu, Jing, Zou, Li, Sun, Yu, Lu, Xuzai, Liu, Li, Miao, Xiaoping, Xiong, Guanglian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617174/ https://www.ncbi.nlm.nih.gov/pubmed/23593147 http://dx.doi.org/10.1371/journal.pone.0059570

Ejemplares similares

Folate-related gene variants in Irish families affected by neural tube defects
por: Fisk Green, Ridgely, et al.
Publicado: (2013)

Neural Tube Defects and Folate Deficiency: Is DNA Repair Defective?
por: Wang, Xiuwei, et al.
Publicado: (2023)

Neural tube defects between folate metabolism and genetics
por: Alfarra, Helmi Y., et al.
Publicado: (2011)

Periconceptional Folate Deficiency and Implications in Neural Tube Defects
por: Safi, J., et al.
Publicado: (2012)

MNS16A Tandem Repeats Minisatellite of Human Telomerase Gene and Cancer Risk: A Meta-Analysis
por: Xia, Xiaoping, et al.
Publicado: (2013)

Folate Deficiency and Folic Acid Supplementation: The Prevention of Neural-Tube Defects and Congenital Heart Defects
por: Czeizel, Andrew E., et al.
Publicado: (2013)

Population red blood cell folate concentrations for prevention of neural tube defects: bayesian model
por: Crider, Krista S, et al.
Publicado: (2014)

HEALTH PROMOTION IN A PRIMARY HEALTH CARE SETTING: Neural Tube Defects and Folate
por: French, Simon D.
Publicado: (1997)

Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects
por: Blom, Henk J., et al.
Publicado: (2010)

Intergenerational association of gut microbiota and metabolism with perinatal folate metabolism and neural tube defects
por: Wang, Shan, et al.
Publicado: (2023)

Genomic DNA Hypomethylation Is Associated with Neural Tube Defects Induced by Methotrexate Inhibition of Folate Metabolism
por: Wang, Xiuwei, et al.
Publicado: (2015)

Abnormal transcriptome-wide DNA demethylation induced by folate deficiency causes neural tube defects
por: Wang, Shan, et al.
Publicado: (2022)

Polymorphisms in Maternal Selected Folate Metabolism-Related Genes in Neural Tube Defect-Affected Pregnancy
por: Dewelle, Winner K., et al.
Publicado: (2023)

Folate deficiency disturbs hsa‐let‐7 g level through methylation regulation in neural tube defects
por: Wang, Li, et al.
Publicado: (2017)

The impact of voluntary folate fortification of corn masa flour on US pregnancies complicated by neural tube defects
por: Khalid, Syed I., et al.
Publicado: (2023)

Barriers and facilitators to the implementation of mandatory folate fortification as an evidence-based policy to prevent neural tube defects
por: Ghotme, Kemel A., et al.
Publicado: (2023)

Functional Validation of CLDN Variants Identified in a Neural Tube Defect Cohort Demonstrates Their Contribution to Neural Tube Defects
por: Baumholtz, Amanda I., et al.
Publicado: (2020)

Folate deficiency induced H2A ubiquitination to lead to downregulated expression of genes involved in neural tube defects
por: Pei, Pei, et al.
Publicado: (2019)

Public health failure in the prevention of neural tube defects: time to abandon the tolerable upper intake level of folate
por: Wald, Nicholas J., et al.
Publicado: (2018)

Folate Status and Neural Tube Defects in Aboriginal Australians: the Success of Mandatory Fortification in Reducing a Health Disparity
por: D'Antoine, Heather, et al.
Publicado: (2019)

Folate Status and Neural Tube Defects in Aboriginal Australians: the Success of Mandatory Fortification in Reducing a Health Disparity
Publicado: (2020)

Red Blood Cell Folate Likely Overestimated in Australian National Survey: Implications for Neural Tube Defect Risk
por: Hunt, Shannon E., et al.
Publicado: (2020)

The Unresolved Tragedy of Neural-Tube Defects in India: The Case for Folate- and Vitamin-B(12)-Fortified Tea for Prevention
por: Vora, Ravindra Motilal, et al.
Publicado: (2022)

Folate Pathway Gene Single Nucleotide Polymorphisms and Neural Tube Defects: A Systematic Review and Meta-Analysis
por: Almekkawi, Ahmad K., et al.
Publicado: (2022)

Aberrant Gcm1 expression mediates Wnt/β-catenin pathway activation in folate deficiency involved in neural tube defects
por: Li, Jianting, et al.
Publicado: (2021)

Variants identified in PTK7 associated with neural tube defects
por: Lei, Yunping, et al.
Publicado: (2019)

Eph and Ephrin Variants in Malaysian Neural Tube Defect Families
por: Mohd-Zin, Siti Waheeda, et al.
Publicado: (2022)

Neural Tube Defects and Folate Pathway Genes: Family-Based Association Tests of Gene–Gene and Gene–Environment Interactions
por: Boyles, Abee L., et al.
Publicado: (2006)

Maternal Folate and Vitamin B(12) Status and Neural Tube Defects in Northern Iran: A Case Control Study
por: Mobasheri, Elahm, et al.
Publicado: (2010)

Folate, Vitamin B12, and Homocysteine Levels in Women With Neural Tube Defect-Affected Pregnancy in Addis Ababa, Ethiopia
por: Kucha, Winner, et al.
Publicado: (2022)

The Genetic Variant on Chromosome 10p14 Is Associated with Risk of Colorectal Cancer: Results from a Case-Control Study and a Meta-Analysis
por: Qin, Qin, et al.
Publicado: (2013)

The association and significance of H3K27me3 and a folate metabolic gene ACat2 in neural tube defects
por: Zhai, Sifan, et al.
Publicado: (2016)

Association between rare variants in specific functional pathways and human neural tube defects multiple subphenotypes
por: Zou, Jizhen, et al.
Publicado: (2020)

Inositol, neural tube closure and the prevention of neural tube defects
por: Greene, Nicholas D.E., et al.
Publicado: (2017)

Threshold for neural tube defect risk by accumulated singleton loss-of-function variants
por: Chen, Zhongzhong, et al.
Publicado: (2018)

Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia
por: Farkas, Sanja A., et al.
Publicado: (2013)

Somatic and de novo Germline Variants of MEDs in Human Neural Tube Defects
por: Tian, Tian, et al.
Publicado: (2021)

Clomiphene and neural tube defects.
por: Nevin, N. C., et al.
Publicado: (1976)

Epidemiology of neural tube defects
por: Al-Mendalawi, Mahmood D.
Publicado: (2015)

Epidemiology of neural tube defects
por: Seidahmed, Mohammed Z., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_kub8774unrfuij1m6rdn4goib2