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PKR-Like Endoplasmic Reticulum Kinase Is Necessary for Lipogenic Activation during HCMV Infection

PKR-like endoplasmic reticulum (ER) kinase (PERK) is an ER-associated stress sensor protein which phosphorylates eukaryotic initiation factor 2α (eIF2α) to induce translation attenuation in response to ER stress. PERK is also a regulator of lipogenesis during adipocyte differentiation through activa...

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Detalles Bibliográficos
Autores principales:	Yu, Yongjun, Pierciey, Francis J., Maguire, Tobi G., Alwine, James C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617203/ https://www.ncbi.nlm.nih.gov/pubmed/23592989 http://dx.doi.org/10.1371/journal.ppat.1003266

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