Cargando…

Mobile Genetic Element SCCmec-encoded psm-mec RNA Suppresses Translation of agrA and Attenuates MRSA Virulence

Community acquired-methicillin resistant Staphylococcus aureus (CA-MRSA) is a socially problematic pathogen that infects healthy individuals, causing severe disease. CA-MRSA is more virulent than hospital associated-MRSA (HA-MRSA). The underlying mechanism for the high virulence of CA-MRSA is not kn...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaito, Chikara, Saito, Yuki, Ikuo, Mariko, Omae, Yosuke, Mao, Han, Nagano, Gentaro, Fujiyuki, Tomoko, Numata, Shunsuke, Han, Xiao, Obata, Kazuaki, Hasegawa, Setsuo, Yamaguchi, Hiroki, Inokuchi, Koiti, Ito, Teruyo, Hiramatsu, Keiichi, Sekimizu, Kazuhisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617227/ https://www.ncbi.nlm.nih.gov/pubmed/23592990 http://dx.doi.org/10.1371/journal.ppat.1003269

Ejemplares similares

Transcription and Translation Products of the Cytolysin Gene psm-mec on the Mobile Genetic Element SCCmec Regulate Staphylococcus aureus Virulence
por: Kaito, Chikara, et al.
Publicado: (2011)

Inhibition of Exotoxin Production by Mobile Genetic Element SCCmec-Encoded psm-mec RNA Is Conserved in Staphylococcal Species
por: Ikuo, Mariko, et al.
Publicado: (2014)

A Novel Gene, fudoh, in the SCCmec Region Suppresses the Colony Spreading Ability and Virulence of Staphylococcus aureus
por: Kaito, Chikara, et al.
Publicado: (2008)

Inhibiting PSMα-induced neutrophil necroptosis protects mice with MRSA pneumonia by blocking the agr system
por: Zhou, Ying, et al.
Publicado: (2018)

Identification and characterization of SCCmec typing with psm-mec positivity in staphylococci from patients with coagulase-negative staphylococci peritoneal dialysis-related peritonitis
por: Zhou, Jun, et al.
Publicado: (2023)

ST9 MRSA strains carrying a variant of type IX SCCmec identified in the Thai community
por: Lulitanond, Aroonlug, et al.
Publicado: (2013)

Detection of mecA and enterotoxin genes in Staphylococcus aureus isolates associated with bovine mastitis and characterization of Staphylococcal cassette chromosome mec (SCCmec) in MRSA strains.
por: Havaei, Seyed Asghar, et al.
Publicado: (2015)

Redox Regulation of the Quorum-sensing Transcription Factor AgrA by Coenzyme A
por: Baković, Jovana, et al.
Publicado: (2021)

Current Status of Staphylococcal Cassette Chromosome mec (SCCmec)
por: Uehara, Yuki
Publicado: (2022)

Difference in agr Dysfunction and Reduced Vancomycin Susceptibility between MRSA Bacteremia Involving SCCmec Types IV/IVa and I–III
por: Jang, Hee-Chang, et al.
Publicado: (2012)

A novel hybrid SCCmec-mecC region in Staphylococcus sciuri
por: Harrison, Ewan M., et al.
Publicado: (2014)

Silence as a way of niche adaptation: mecC-MRSA with variations in the accessory gene regulator (agr) functionality express kaleidoscopic phenotypes
por: Huber, Charlotte, et al.
Publicado: (2020)

Conformational features of the Staphylococcus aureus AgrA-promoter interactions rationalize quorum-sensing triggered gene expression
por: Rajasree, Kalagiri, et al.
Publicado: (2016)

Impact of agr dysfunction on virulence profiles and infections associated with a novel methicillin-resistant Staphylococcus aureus (MRSA) variant of the lineage ST1-SCCmec IV
por: Ferreira, Fabienne Antunes, et al.
Publicado: (2013)

MRSA Harboring mecA Variant Gene mecC, France
por: Laurent, Frederic, et al.
Publicado: (2012)

PSM-Mec—A Virulence Determinant that Connects Transcriptional Regulation, Virulence, and Antibiotic Resistance in Staphylococci
por: Qin, Li, et al.
Publicado: (2016)

Staphylococcal Cassette Chromosome mec in MRSA, Taiwan
por: Wang, Jann-Tay, et al.
Publicado: (2007)

MRSA carrying mecC in captive mara
por: Espinosa-Gongora, C., et al.
Publicado: (2015)

Systematic mutational analysis of the LytTR DNA binding domain of Staphylococcus aureus virulence gene transcription factor AgrA
por: Nicod, Sophie S., et al.
Publicado: (2014)

Small-molecule AgrA inhibitors F12 and F19 act as antivirulence agents against Gram-positive pathogens
por: Greenberg, Michael, et al.
Publicado: (2018)

Inactivation of the Response Regulator AgrA Has a Pleiotropic Effect on Biofilm Formation, Pathogenesis and Stress Response in Staphylococcus lugdunensis
por: Aubourg, Marion, et al.
Publicado: (2022)

Cinnamaldehyde Targets the LytTR DNA-Binding Domain of the Response Regulator AgrA to Attenuate Biofilm Formation of Listeria monocytogenes
por: Jiang, Xiaobing, et al.
Publicado: (2023)

First mecC and mecA Positive Livestock-Associated Methicillin Resistant Staphylococcus aureus (mecC MRSA/LA-MRSA) from Dairy Cattle in Malaysia
por: Aklilu, Erkihun, et al.
Publicado: (2020)

Role of SCCmec type in resistance to the synergistic activity of oxacillin and cefoxitin in MRSA
por: Reichmann, Nathalie T., et al.
Publicado: (2017)

IANCON 2015: Agra
por: Khadilkar, Satish V
Publicado: (2015)

Report of mecC-carrying MRSA in domestic swine
por: Angen, Ø., et al.
Publicado: (2017)

Sepsis 2016 Agra, India: Agra, India. 5-6 February 2016
por: Sharma, Surinder Kumar, et al.
Publicado: (2016)

Distribution and Regulation of the Mobile Genetic Element-Encoded Phenol-Soluble Modulin PSM-mec in Methicillin-Resistant Staphylococcus aureus
por: Chatterjee, Som S., et al.
Publicado: (2011)

Genotypic characterization of Staphylococcus aureus isolated from a burn centre by using agr, spa and SCCmec typing methods
por: Abbasian, S., et al.
Publicado: (2018)

Whole genome sequencing identifies zoonotic transmission of MRSA isolates with the novel mecA homologue mecC
por: Harrison, Ewan M, et al.
Publicado: (2013)

CC8 MRSA Strains Harboring SCCmec Type IVc are Predominant in Colombian Hospitals
por: Jiménez, J. Natalia, et al.
Publicado: (2012)

Identification of Staphylococcus aureus Colony-Spreading Stimulatory Factors from Mammalian Serum
por: Omae, Yosuke, et al.
Publicado: (2014)

Diversity of SCCmec elements and spa types in South African Staphylococcus aureus mecA-positive blood culture isolates
por: Singh-Moodley, Ashika, et al.
Publicado: (2020)

Investigating the relation between resistance pattern and type of Staphylococcal cassette chromosome mec (SCCmec) in methicillin-resistant Staphylococcus aureus
por: Youssef, Christiana Rezk Bottros, et al.
Publicado: (2022)

Determination of Virulence Factors and Resistance Profile of Methicillin-Resistant Staphylococcus aureus Strains among Different Types of spa, agr, and SCCmec
por: Latifpour, Mohammad, et al.
Publicado: (2022)

Comparative Genomic Analysis of Staphylococcal Cassette Chromosome mec Type V Staphylococcus aureus Strains and Estimation of the Emergence of SCCmec V Clinical Isolates in Korea
por: Takahashi, Takashi, et al.
Publicado: (2024)

Human mecC-Carrying MRSA: Clinical Implications and Risk Factors
por: Lozano, Carmen, et al.
Publicado: (2020)

mecC MRSA in Israel—genomic analysis, prevalence and global perspective
por: Baum, Moti, et al.
Publicado: (2022)

Composite SCCmec Element in Single-locus Variant (ST217) of Epidemic MRSA-15 Clone
por: Vignaroli, Carla, et al.
Publicado: (2014)

AGRA: analysis of gene ranking algorithms
por: Kocbek, Simon, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_g9gueea5o1m8feee8lskioq9il