Cargando…

Stress Degradation Behavior of Atorvastatin Calcium and Development of a Suitable Stability-Indicating LC Method for the Determination of Atorvastatin, its Related Impurities, and its Degradation Products

A rapid, reversed-phase liquid chromatographic method was developed for the quantitative determination of Atorvastatin calcium, its related substances (12 impurities), and degradation impurities in bulk drugs. The chromatographic separation was achieved on a Zorbax Bonus-RP column by employing a gra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vukkum, Pallavi, Moses Babu, J., Muralikrishna, R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617653/ https://www.ncbi.nlm.nih.gov/pubmed/23641331 http://dx.doi.org/10.3797/scipharm.1208-06

Ejemplares similares

Stress Degradation Behavior of Abacavir Sulfate and Development of a Suitable Stability-Indicating UHPLC Method for the Determination of Abacavir, its Related Substances, and Degradation Products
por: Vukkum, Pallavi, et al.
Publicado: (2012)

Simultaneous Determination of Atorvastatin and Aspirin in Human Plasma by LC–MS/MS: Its Pharmacokinetic Application
por: Gajula, Ramakrishna, et al.
Publicado: (2012)

Stability-indicating assay method for determination of actarit, its process related impurities and degradation products: Insight into stability profile and degradation pathways(☆)()
por: Abiramasundari, A., et al.
Publicado: (2014)

Novel microwell-based spectrophotometric assay for determination of atorvastatin calcium in its pharmaceutical formulations
por: Wani, Tanveer A, et al.
Publicado: (2011)

Characterization of two new degradation products of atorvastatin calcium formed upon treatment with strong acids
por: Krauß, Jürgen, et al.
Publicado: (2019)

Stability Indicating RP-HPLC Estimation of Atorvastatin Calcium and Amlodipine Besylate in Pharmaceutical Formulations
por: Shah, D. A., et al.
Publicado: (2008)

Degradation Kinetics of Atorvastatin under Stress Conditions and Chemical Analysis by HPLC
por: Oliveira, Marcelo Antonio, et al.
Publicado: (2013)

Dissolution Enhancement of Atorvastatin Calcium by Cocrystallization
por: Al-Kazemi, Reham, et al.
Publicado: (2019)

Spectroscopic studies on photodegradation of atorvastatin calcium
por: Oprica, Madalina, et al.
Publicado: (2021)

Degradation Pathway for Eplerenone by Validated Stability Indicating UP-LC Method
por: Sudhakar Babu, Kondru, et al.
Publicado: (2012)

Effects of Danshen tablets on pharmacokinetics of atorvastatin calcium in rats and its potential mechanism
por: Sun, Sen, et al.
Publicado: (2018)

Simultaneous determination of atorvastatin, metformin and glimepiride in human plasma by LC–MS/MS and its application to a human pharmacokinetic study
por: Polagani, Srinivasa Rao, et al.
Publicado: (2013)

Spectrophotometric and TLC-densitometric methods for the simultaneous determination of Ezetimibe and Atorvastatin calcium
por: Baghdady, Yehia Z., et al.
Publicado: (2013)

An improved kilogram-scale preparation of atorvastatin calcium
por: Novozhilov, Yuri V, et al.
Publicado: (2015)

Comments on "Dissolution Enhancement of Atorvastatin Calcium by Cocrystallization"
por: Emami, Shahram, et al.
Publicado: (2021)

Atorvastatin Modulates the Efficacy of Electroporation and Calcium Electrochemotherapy
por: Szlasa, Wojciech, et al.
Publicado: (2021)

Stability Indicating RP-HPLC Method for the Simultaneous Determination of Atorvastatin Calcium, Metformin Hydrochloride, and Glimepiride in Bulk and Combined Tablet Dosage Form
por: Ramesh, Devi, et al.
Publicado: (2014)

A Validated Stability-Indicating Liquid Chromatographic Method for Determination of Degradation Impurities and Diastereomers in Voriconazole Tablets
por: Shaikh, Kabeer A., et al.
Publicado: (2012)

Simultaneous Quantitative Determination of Metoprolol, Atorvastatin and Ramipril in Capsules by a Validated Stability-Indicating RP-UPLC Method
por: Seshadri, Raja Kumar, et al.
Publicado: (2010)

Atorvastatin-Induced Necrotizing Myopathy and its Response to Combination Therapy
por: Boppana, Sri Harsha, et al.
Publicado: (2021)

Atorvastatin-induced pancreatitis
por: Prajapati, Samir, et al.
Publicado: (2010)

Atorvastatin (Lipitor) by MCR
por: Zarganes-Tzitzikas, Tryfon, et al.
Publicado: (2019)

Influence of Drug–Drug Interactions on the Pharmacokinetics of Atorvastatin and Its Major Active Metabolite ortho-OH-Atorvastatin in Aging People Living with HIV
por: Courlet, Perrine, et al.
Publicado: (2020)

Validated stability indicating methods for determination of nitazoxanide in presence of its degradation products()
por: Ali, Nouruddin W., et al.
Publicado: (2012)

Drug Resinates an Attractive Approach of Solubility Enhancement of Atorvastatin Calcium
por: Kulthe, V. V., et al.
Publicado: (2013)

Development of Atorvastatin Calcium Biloaded Capsules for Oral Administration of Hypercholesterolemia
por: Senthilvel, Chitra Karthikeyini, et al.
Publicado: (2022)

Synchronized separation of atorvastatin—an antihyperlipidemic drug with antihypertensive, antidiabetic, antithrombotic drugs by RP-LC for determination in combined formulations
por: Talluri, M.V.N. Kumar, et al.
Publicado: (2012)

A stability indicating HPLC method for determination of mebeverine in the presence of its degradation products and kinetic study of its degradation in oxidative condition
por: Souri, E., et al.
Publicado: (2014)

Validated spectrofluorimetric method for the determination of atorvastatin in pharmaceutical preparations
por: Sharaf El-Din, Mohie M.K., et al.
Publicado: (2012)

Validated spectral manipulations for determination of an anti-neoplastic drug and its related impurities including its hazardous degradation product
por: Naguib, Ibrahim A., et al.
Publicado: (2021)

Identification of degradation impurity of TGR5 receptor agonist-ZY12201 by LC–MS technique during force degradation study
por: Sojitra, Chandrakant, et al.
Publicado: (2021)

Forced Degradation Behaviour of Fluphenazine Hydrochloride by LC and Characterization of its Oxidative Degradation Product by LC–MS/MS
por: Thummar, Kashyap N., et al.
Publicado: (2015)

Characterisation and evaluation of pharmaceutical solvates of Atorvastatin calcium by thermoanalytical and spectroscopic studies
por: Chadha, Renu, et al.
Publicado: (2012)

Physically Targeted Intravenous Polyurethane Nanoparticles for Controlled Release of Atorvastatin Calcium
por: Eftekhari, Behnaz Sadat, et al.
Publicado: (2017)

Retracted: Development of Atorvastatin Calcium Biloaded Capsules for Oral Administration of Hypercholesterolemia
por: and Alternative Medicine, Evidence-Based Complementary
Publicado: (2023)

Atorvastatin-induced acute pancreatitis
por: Deshpande, Prasanna R., et al.
Publicado: (2011)

Bioenhancing effects of naringin on atorvastatin
por: Sama, Venkatesh, et al.
Publicado: (2019)

Atorvastatin-Induced Refractory Thrombocytopenia
por: Ghuman, Jasmine, et al.
Publicado: (2021)

Stress Degradation Studies of Tebipenem and a Validated Stability-Indicating LC Method
por: Cielecka-Piontek, Judyta, et al.
Publicado: (2012)

Comprehensive Assessment of Degradation Behavior of Aspirin and Atorvastatin Singly and in Combination by Using a Validated RP-HPLC Method
por: Sherikar, Omkar, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_6j2v2to21lefhh3922qt8fc05c