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Chromatographic Behaviour Predicts the Ability of Potential Nootropics to Permeate the Blood-Brain Barrier
The log BB parameter is the logarithm of the ratio of a compound’s equilibrium concentrations in the brain tissue versus the blood plasma. This parameter is a useful descriptor in assessing the ability of a compound to permeate the blood-brain barrier. The aim of this study was to develop a Hansch-t...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Österreichische Apotheker-Verlagsgesellschaft
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617654/ https://www.ncbi.nlm.nih.gov/pubmed/23641330 http://dx.doi.org/10.3797/scipharm.1208-19 |