A coherent model for turbid imaging with confocal microscopy

We present an engineering model of coherent imaging within a turbid volume, such as human tissues, with a confocal microscope. The model is built to analyze the statistical effect of aberrations and multiply scattered light on the resulting image. Numerical modeling of theory is compared with experi...

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Detalles Bibliográficos
Autores principales: Glazowski, Christopher E., Zavislan, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2013
Materias:
Optics of Tissue and Turbid Media
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617712/
https://www.ncbi.nlm.nih.gov/pubmed/23577285
http://dx.doi.org/10.1364/BOE.4.000500
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author Glazowski, Christopher E.
Zavislan, James
author_facet Glazowski, Christopher E.
Zavislan, James
author_sort Glazowski, Christopher E.
collection PubMed
description We present an engineering model of coherent imaging within a turbid volume, such as human tissues, with a confocal microscope. The model is built to analyze the statistical effect of aberrations and multiply scattered light on the resulting image. Numerical modeling of theory is compared with experimental results. We describe the construction of a stable phantom that represents the statistical effect of object turbidity on the image recorded. The model and phantom can serve as basis for system optimization in turbid imaging.
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spelling pubmed-36177122013-04-10 A coherent model for turbid imaging with confocal microscopy Glazowski, Christopher E. Zavislan, James Biomed Opt Express Optics of Tissue and Turbid Media We present an engineering model of coherent imaging within a turbid volume, such as human tissues, with a confocal microscope. The model is built to analyze the statistical effect of aberrations and multiply scattered light on the resulting image. Numerical modeling of theory is compared with experimental results. We describe the construction of a stable phantom that represents the statistical effect of object turbidity on the image recorded. The model and phantom can serve as basis for system optimization in turbid imaging. Optical Society of America 2013-03-04 /pmc/articles/PMC3617712/ /pubmed/23577285 http://dx.doi.org/10.1364/BOE.4.000500 Text en © 2013 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Optics of Tissue and Turbid Media
Glazowski, Christopher E.
Zavislan, James
A coherent model for turbid imaging with confocal microscopy
title A coherent model for turbid imaging with confocal microscopy
title_full A coherent model for turbid imaging with confocal microscopy
title_fullStr A coherent model for turbid imaging with confocal microscopy
title_full_unstemmed A coherent model for turbid imaging with confocal microscopy
title_short A coherent model for turbid imaging with confocal microscopy
title_sort coherent model for turbid imaging with confocal microscopy
topic Optics of Tissue and Turbid Media
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617712/
https://www.ncbi.nlm.nih.gov/pubmed/23577285
http://dx.doi.org/10.1364/BOE.4.000500
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