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Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT

Joint-aperture optical coherence tomography (JA-OCT) is an angle-resolved OCT method, in which illumination from an active channel is simultaneously probed by several passive channels. JA-OCT increases the collection efficiency and effective sensitivity of the OCT system without increasing the power...

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Autores principales: Klein, Thomas, André, Raphael, Wieser, Wolfgang, Pfeiffer, Tom, Huber, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617723/
https://www.ncbi.nlm.nih.gov/pubmed/23577296
http://dx.doi.org/10.1364/BOE.4.000619
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author Klein, Thomas
André, Raphael
Wieser, Wolfgang
Pfeiffer, Tom
Huber, Robert
author_facet Klein, Thomas
André, Raphael
Wieser, Wolfgang
Pfeiffer, Tom
Huber, Robert
author_sort Klein, Thomas
collection PubMed
description Joint-aperture optical coherence tomography (JA-OCT) is an angle-resolved OCT method, in which illumination from an active channel is simultaneously probed by several passive channels. JA-OCT increases the collection efficiency and effective sensitivity of the OCT system without increasing the power on the sample. Additionally, JA-OCT provides angular scattering information about the sample in a single acquisition, so the OCT imaging speed is not reduced. Thus, JA-OCT is especially suitable for ultra high speed in-vivo imaging. JA-OCT is compared to other angle-resolved techniques, and the relation between joint aperture imaging, adaptive optics, coherent and incoherent compounding is discussed. We present angle-resolved imaging of the human retina at an axial scan rate of 1.68 MHz, and demonstrate the benefits of JA-OCT: Speckle reduction, signal increase and suppression of specular and parasitic reflections. Moreover, in the future JA-OCT may allow for the reconstruction of the full Doppler vector and tissue discrimination by analysis of the angular scattering dependence.
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spelling pubmed-36177232013-04-10 Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT Klein, Thomas André, Raphael Wieser, Wolfgang Pfeiffer, Tom Huber, Robert Biomed Opt Express Optical Coherence Tomography Joint-aperture optical coherence tomography (JA-OCT) is an angle-resolved OCT method, in which illumination from an active channel is simultaneously probed by several passive channels. JA-OCT increases the collection efficiency and effective sensitivity of the OCT system without increasing the power on the sample. Additionally, JA-OCT provides angular scattering information about the sample in a single acquisition, so the OCT imaging speed is not reduced. Thus, JA-OCT is especially suitable for ultra high speed in-vivo imaging. JA-OCT is compared to other angle-resolved techniques, and the relation between joint aperture imaging, adaptive optics, coherent and incoherent compounding is discussed. We present angle-resolved imaging of the human retina at an axial scan rate of 1.68 MHz, and demonstrate the benefits of JA-OCT: Speckle reduction, signal increase and suppression of specular and parasitic reflections. Moreover, in the future JA-OCT may allow for the reconstruction of the full Doppler vector and tissue discrimination by analysis of the angular scattering dependence. Optical Society of America 2013-03-28 /pmc/articles/PMC3617723/ /pubmed/23577296 http://dx.doi.org/10.1364/BOE.4.000619 Text en ©2013 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Optical Coherence Tomography
Klein, Thomas
André, Raphael
Wieser, Wolfgang
Pfeiffer, Tom
Huber, Robert
Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT
title Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT
title_full Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT
title_fullStr Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT
title_full_unstemmed Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT
title_short Joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic MHz OCT
title_sort joint aperture detection for speckle reduction and increased collection efficiency in ophthalmic mhz oct
topic Optical Coherence Tomography
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617723/
https://www.ncbi.nlm.nih.gov/pubmed/23577296
http://dx.doi.org/10.1364/BOE.4.000619
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