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Hepatocyte-targeting gene transfer mediated by galactosylated poly(ethylene glycol)-graft-polyethylenimine derivative

Biscarbamate cross-linked polyethylenimine derivative (PEI-Et) has been reported as a novel nonviral vector for efficient and safe gene transfer in our previous work. However, it had no cell-specificity. To achieve specific delivery of genes to hepatocytes, galactosylated poly(ethylene glycol)-graft...

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Detalles Bibliográficos
Autores principales: Wang, Yuqiang, Su, Jing, Cai, Wenwei, Lu, Ping, Yuan, Lifen, Jin, Tuo, Chen, Shuyan, Sheng, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617917/
https://www.ncbi.nlm.nih.gov/pubmed/23576866
http://dx.doi.org/10.2147/DDDT.S42582