Cargando…
Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice
The formation of the atherosclerotic lesion is a complex process influenced by an array of inflammatory and lipid metabolism pathways. We previously demonstrated that NR4A nuclear receptors are highly induced in macrophages in response to inflammatory stimuli and modulate the expression of genes lin...
Autores principales: | Chao, Lily C., Soto, Erin, Hong, Cynthia, Ito, Ayaka, Pei, Liming, Chawla, Ajay, Conneely, Orla M., Tangirala, Rajendra K., Evans, Ronald M., Tontonoz, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular
Biology
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617954/ https://www.ncbi.nlm.nih.gov/pubmed/23288947 http://dx.doi.org/10.1194/jlr.M034157 |
Ejemplares similares
-
Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells
por: Duren, Ryan P., et al.
Publicado: (2016) -
Drug Targeting of NR4A Nuclear Receptors for Treatment of Acute Myeloid Leukemia
por: Boudreaux, Seth P., et al.
Publicado: (2018) -
Nuclear Receptor 4a3 (Nr4a3) Regulates Murine Mast Cell Responses and Granule Content
por: Garcia-Faroldi, Gianni, et al.
Publicado: (2014) -
Adiponectin Expression Protects against Angiotensin II-Mediated Inflammation and Accelerated Atherosclerosis
por: van Stijn, Caroline M. W., et al.
Publicado: (2014) -
Targeting Oncogenic Super Enhancers in MYC-Dependent AML Using a Small Molecule Activator of NR4A Nuclear Receptors
por: Call, S. Greg, et al.
Publicado: (2020)