Development of a Chronic Kidney Disease Model in C57BL/6 Mice with Relevance to Human Pathology

BACKGROUND: Genetically modified mice are used to investigate disease and assess potential interventions. However, research into kidney fibrosis is hampered by a lack of models of chronic kidney disease (CKD) in mice. Recently, aristolochic acid nephropathy (AAN), characterised by severe tubulointer...

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Detalles Bibliográficos
Autores principales: Huang, Linghong, Scarpellini, Alessandra, Funck, Muriel, Verderio, Elisabetta A.M., Johnson, Timothy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617971/
https://www.ncbi.nlm.nih.gov/pubmed/23610565
http://dx.doi.org/10.1159/000346180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617971/
https://www.ncbi.nlm.nih.gov/pubmed/23610565
http://dx.doi.org/10.1159/000346180

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