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Development of a Chronic Kidney Disease Model in C57BL/6 Mice with Relevance to Human Pathology
BACKGROUND: Genetically modified mice are used to investigate disease and assess potential interventions. However, research into kidney fibrosis is hampered by a lack of models of chronic kidney disease (CKD) in mice. Recently, aristolochic acid nephropathy (AAN), characterised by severe tubulointer...
Autores principales: | Huang, Linghong, Scarpellini, Alessandra, Funck, Muriel, Verderio, Elisabetta A.M., Johnson, Timothy S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617971/ https://www.ncbi.nlm.nih.gov/pubmed/23610565 http://dx.doi.org/10.1159/000346180 |
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