Cargando…
Treatment of Esophageal Variceal Hemorrhage with Self-Expanding Metal Stents as a Rescue Maneuver in a Swiss Multicentric Cohort
Acute esophageal variceal bleeding in patients with portal hypertension remains a complication with a high mortality today. In cases refractory to standard therapy including endoscopic band ligation and pharmacological therapy, traditionally balloon tamponade has been used as salvage therapy. Howeve...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617972/ https://www.ncbi.nlm.nih.gov/pubmed/23626509 http://dx.doi.org/10.1159/000350192 |
_version_ | 1782265331471876096 |
---|---|
author | Fierz, Fabienne C. Kistler, Walter Stenz, Volker Gubler, Christoph |
author_facet | Fierz, Fabienne C. Kistler, Walter Stenz, Volker Gubler, Christoph |
author_sort | Fierz, Fabienne C. |
collection | PubMed |
description | Acute esophageal variceal bleeding in patients with portal hypertension remains a complication with a high mortality today. In cases refractory to standard therapy including endoscopic band ligation and pharmacological therapy, traditionally balloon tamponade has been used as salvage therapy. However, these techniques show several important limitations. Self-expanding metal stents (SEMS) have been proposed as an alternative rescue treatment. The use of variceal stenting in 7 patients with a total of 9 bleeding episodes in three different Swiss hospitals is demonstrated. While immediate bleeding control is achieved in a high percentage of cases, the 5-day and 6-week mortality rate remain high. Mortality is strongly influenced by the severity of the underlying liver disease. Accordingly, our data represent a high-risk patient collective. Thanks to their safety and easy handling, SEMS are an interesting alternative to balloon tamponade as a bridging intervention to definitive therapy including the pre-hospital setting. |
format | Online Article Text |
id | pubmed-3617972 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-36179722013-04-26 Treatment of Esophageal Variceal Hemorrhage with Self-Expanding Metal Stents as a Rescue Maneuver in a Swiss Multicentric Cohort Fierz, Fabienne C. Kistler, Walter Stenz, Volker Gubler, Christoph Case Rep Gastroenterol Published online: March, 2013 Acute esophageal variceal bleeding in patients with portal hypertension remains a complication with a high mortality today. In cases refractory to standard therapy including endoscopic band ligation and pharmacological therapy, traditionally balloon tamponade has been used as salvage therapy. However, these techniques show several important limitations. Self-expanding metal stents (SEMS) have been proposed as an alternative rescue treatment. The use of variceal stenting in 7 patients with a total of 9 bleeding episodes in three different Swiss hospitals is demonstrated. While immediate bleeding control is achieved in a high percentage of cases, the 5-day and 6-week mortality rate remain high. Mortality is strongly influenced by the severity of the underlying liver disease. Accordingly, our data represent a high-risk patient collective. Thanks to their safety and easy handling, SEMS are an interesting alternative to balloon tamponade as a bridging intervention to definitive therapy including the pre-hospital setting. S. Karger AG 2013-03-07 /pmc/articles/PMC3617972/ /pubmed/23626509 http://dx.doi.org/10.1159/000350192 Text en Copyright © 2013 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions. |
spellingShingle | Published online: March, 2013 Fierz, Fabienne C. Kistler, Walter Stenz, Volker Gubler, Christoph Treatment of Esophageal Variceal Hemorrhage with Self-Expanding Metal Stents as a Rescue Maneuver in a Swiss Multicentric Cohort |
title | Treatment of Esophageal Variceal Hemorrhage with Self-Expanding Metal Stents as a Rescue Maneuver in a Swiss Multicentric Cohort |
title_full | Treatment of Esophageal Variceal Hemorrhage with Self-Expanding Metal Stents as a Rescue Maneuver in a Swiss Multicentric Cohort |
title_fullStr | Treatment of Esophageal Variceal Hemorrhage with Self-Expanding Metal Stents as a Rescue Maneuver in a Swiss Multicentric Cohort |
title_full_unstemmed | Treatment of Esophageal Variceal Hemorrhage with Self-Expanding Metal Stents as a Rescue Maneuver in a Swiss Multicentric Cohort |
title_short | Treatment of Esophageal Variceal Hemorrhage with Self-Expanding Metal Stents as a Rescue Maneuver in a Swiss Multicentric Cohort |
title_sort | treatment of esophageal variceal hemorrhage with self-expanding metal stents as a rescue maneuver in a swiss multicentric cohort |
topic | Published online: March, 2013 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617972/ https://www.ncbi.nlm.nih.gov/pubmed/23626509 http://dx.doi.org/10.1159/000350192 |
work_keys_str_mv | AT fierzfabiennec treatmentofesophagealvaricealhemorrhagewithselfexpandingmetalstentsasarescuemaneuverinaswissmulticentriccohort AT kistlerwalter treatmentofesophagealvaricealhemorrhagewithselfexpandingmetalstentsasarescuemaneuverinaswissmulticentriccohort AT stenzvolker treatmentofesophagealvaricealhemorrhagewithselfexpandingmetalstentsasarescuemaneuverinaswissmulticentriccohort AT gublerchristoph treatmentofesophagealvaricealhemorrhagewithselfexpandingmetalstentsasarescuemaneuverinaswissmulticentriccohort |