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Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc(−/+) mice

BACKGROUND: Colorectal cancer (CRC) is the second leading cause of death from cancer in the United States. Colorectal cancers have a prolonged latency following initiation that may span decades providing ample time for implementing a chemoprevention strategy that could block or reverse the progressi...

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Detalles Bibliográficos
Autores principales: Karim, Baktiar O, Rhee, Ki-Jong, Liu, Guosheng, Zheng, Dongfeng, Huso, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618006/
https://www.ncbi.nlm.nih.gov/pubmed/23530816
http://dx.doi.org/10.1186/1471-2407-13-157