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Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc(−/+) mice
BACKGROUND: Colorectal cancer (CRC) is the second leading cause of death from cancer in the United States. Colorectal cancers have a prolonged latency following initiation that may span decades providing ample time for implementing a chemoprevention strategy that could block or reverse the progressi...
Autores principales: | Karim, Baktiar O, Rhee, Ki-Jong, Liu, Guosheng, Zheng, Dongfeng, Huso, David L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618006/ https://www.ncbi.nlm.nih.gov/pubmed/23530816 http://dx.doi.org/10.1186/1471-2407-13-157 |
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