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Promoter Characterization and Role of cAMP/PKA/CREB in the Basal Transcription of the Mouse ORMDL3 Gene

Orosomucoid 1-like 3 (ORMDL3) gene was strongly linked with the development of asthma in genetic association studies, and its expression could be significantly induced by allergen in airway epithelial cells of mice. However, the expression mechanism of ORMDL3 was still unclear. Here we have identifi...

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Detalles Bibliográficos
Autores principales: Zhuang, Li-Li, Jin, Rui, Zhu, Liang-Hua, Xu, Hua-Guo, Li, Yue, Gao, Shan, Liu, Jia-Yin, Zhou, Guo-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618037/
https://www.ncbi.nlm.nih.gov/pubmed/23577138
http://dx.doi.org/10.1371/journal.pone.0060630