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Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass

Uterine leiomyosarcoma is a rare malignancy and carries a poorer prognosis when compared to endometrial carcinoma. It has been observed to metastasize to all the major organs. It presents with symptoms of abdominal distension, vaginal bleeding and may pass unnoticed until an advanced stage in patien...

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Autores principales: Marak, Creticus P., Ponea, Ana M., Alappan, Narendrakumar, Shaheen, Shagufta, Guddati, Achuta K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618104/
https://www.ncbi.nlm.nih.gov/pubmed/23569446
http://dx.doi.org/10.1159/000346935
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author Marak, Creticus P.
Ponea, Ana M.
Alappan, Narendrakumar
Shaheen, Shagufta
Guddati, Achuta K.
author_facet Marak, Creticus P.
Ponea, Ana M.
Alappan, Narendrakumar
Shaheen, Shagufta
Guddati, Achuta K.
author_sort Marak, Creticus P.
collection PubMed
description Uterine leiomyosarcoma is a rare malignancy and carries a poorer prognosis when compared to endometrial carcinoma. It has been observed to metastasize to all the major organs. It presents with symptoms of abdominal distension, vaginal bleeding and may pass unnoticed until an advanced stage in patients with leiomyomas. Surgery is a viable option in patients with disease limited to the uterus, but metastasis to the heart may require surgery to prevent acute and catastrophic complications. The case described here involves metastasis to the tricuspid valve, which caused severe tricuspid regurgitation in the setting of acute pulmonary embolism. Surgical resection restored cardiac function and stabilized the patient. This case illustrates a rare site of metastasis of leiomyosarcoma which required immediate intervention and resulted in a favorable outcome.
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spelling pubmed-36181042013-04-08 Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass Marak, Creticus P. Ponea, Ana M. Alappan, Narendrakumar Shaheen, Shagufta Guddati, Achuta K. Case Rep Oncol Published online: February, 2013 Uterine leiomyosarcoma is a rare malignancy and carries a poorer prognosis when compared to endometrial carcinoma. It has been observed to metastasize to all the major organs. It presents with symptoms of abdominal distension, vaginal bleeding and may pass unnoticed until an advanced stage in patients with leiomyomas. Surgery is a viable option in patients with disease limited to the uterus, but metastasis to the heart may require surgery to prevent acute and catastrophic complications. The case described here involves metastasis to the tricuspid valve, which caused severe tricuspid regurgitation in the setting of acute pulmonary embolism. Surgical resection restored cardiac function and stabilized the patient. This case illustrates a rare site of metastasis of leiomyosarcoma which required immediate intervention and resulted in a favorable outcome. S. Karger AG 2013-02-28 /pmc/articles/PMC3618104/ /pubmed/23569446 http://dx.doi.org/10.1159/000346935 Text en Copyright © 2013 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: February, 2013
Marak, Creticus P.
Ponea, Ana M.
Alappan, Narendrakumar
Shaheen, Shagufta
Guddati, Achuta K.
Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass
title Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass
title_full Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass
title_fullStr Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass
title_full_unstemmed Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass
title_short Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass
title_sort uterine leiomyosarcoma manifesting as a tricuspid valve mass
topic Published online: February, 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618104/
https://www.ncbi.nlm.nih.gov/pubmed/23569446
http://dx.doi.org/10.1159/000346935
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