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Population-Based Input Function Modeling for [(18)F]FMPEP-d (2), an Inverse Agonist Radioligand for Cannabinoid CB(1) Receptors: Validation in Clinical Studies
BACKGROUND: Population-based input function (PBIF) may be a valid alternative to full blood sampling for quantitative PET imaging. PBIF is typically validated by comparing its quantification results with those obtained via arterial sampling. However, for PBIF to be employed in actual clinical resear...
Autores principales: | Zanotti-Fregonara, Paolo, Hirvonen, Jussi, Lyoo, Chul Hyoung, Zoghbi, Sami S., Rallis-Frutos, Denise, Huestis, Marilyn A., Morse, Cheryl, Pike, Victor W., Innis, Robert B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618181/ https://www.ncbi.nlm.nih.gov/pubmed/23577094 http://dx.doi.org/10.1371/journal.pone.0060231 |
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