Amelioration of Behavioral Abnormalities in BH(4)-deficient Mice by Dietary Supplementation of Tyrosine

This study reports an amelioration of abnormal motor behaviors in tetrahydrobiopterin (BH(4))-deficient Spr (−/−) mice by the dietary supplementation of tyrosine. Since BH(4) is an essential cofactor for the conversion of phenylalanine into tyrosine as well as the synthesis of dopamine neurotransmit...

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Detalles Bibliográficos
Autores principales: Kwak, Sang Su, Jeong, Mikyoung, Choi, Ji Hye, Kim, Daesoo, Min, Hyesun, Yoon, Yoosik, Hwang, Onyou, Meadows, Gary G., Joe, Cheol O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618182/
https://www.ncbi.nlm.nih.gov/pubmed/23577163
http://dx.doi.org/10.1371/journal.pone.0060803

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