RNAi-Mediated Silencing of Atp6i and Atp6i Haploinsufficiency Prevents Both Bone Loss and Inflammation in a Mouse Model of Periodontal Disease

Periodontal disease affects about 80% of adults in America, and is characterized by oral bacterial infection-induced gingival inflammation, oral bone resorption, and tooth loss. Periodontitis is also associated with other diseases such as rheumatoid arthritis, diabetes, and heart disease. Although m...

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Detalles Bibliográficos
Autores principales: Jiang, Hongbing, Chen, Wei, Zhu, Guochun, Zhang, Lijie, Tucker, Byron, Hao, Liang, Feng, Shengmei, Ci, Hongliang, Ma, Junqing, Wang, Lin, Stashenko, Philip, Li, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618217/
https://www.ncbi.nlm.nih.gov/pubmed/23577057
http://dx.doi.org/10.1371/journal.pone.0058599

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