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An Innovative Strategy for Dual Inhibitor Design and Its Application in Dual Inhibition of Human Thymidylate Synthase and Dihydrofolate Reductase Enzymes

Due to the diligence of inherent redundancy and robustness in many biological networks and pathways, multitarget inhibitors present a new prospect in the pharmaceutical industry for treatment of complex diseases. Nevertheless, to design multitarget inhibitors is concurrently a great challenge for me...

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Detalles Bibliográficos
Autores principales:	Arooj, Mahreen, Sakkiah, Sugunadevi, Cao, Guang ping, Lee, Keun Woo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618229/ https://www.ncbi.nlm.nih.gov/pubmed/23577115 http://dx.doi.org/10.1371/journal.pone.0060470

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