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Rule-based multi-scale simulation for drug effect pathway analysis
BACKGROUND: Biological systems are robust and complex to maintain stable phenotypes under various conditions. In these systems, drugs reported the limited efficacy and unexpected side-effects. To remedy this situation, many pharmaceutical laboratories have begun to research combination drugs and som...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618249/ https://www.ncbi.nlm.nih.gov/pubmed/23566173 http://dx.doi.org/10.1186/1472-6947-13-S1-S4 |