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HP1γ expression is elevated in prostate cancer and is superior to Gleason score as a predictor of biochemical recurrence after radical prostatectomy

BACKGROUND: Aberrant chromatin structure in cancer cells results from altered proteins involved in its packaging. Heterochromatin protein 1 gamma (HP1γ) is a non-histone heterochromatic protein that functions to maintain chromatin stability and is important in embryonic development. Given an interes...

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Detalles Bibliográficos
Autores principales: Slezak, Jon, Truong, Matthew, Huang, Wei, Jarrard, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618256/
https://www.ncbi.nlm.nih.gov/pubmed/23522301
http://dx.doi.org/10.1186/1471-2407-13-148