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Genome-Scale Screening of Drug-Target Associations Relevant to K(i) Using a Chemogenomics Approach

The identification of interactions between drugs and target proteins plays a key role in genomic drug discovery. In the present study, the quantitative binding affinities of drug-target pairs are differentiated as a measurement to define whether a drug interacts with a protein or not, and then a che...

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Detalles Bibliográficos
Autores principales: Cao, Dong-Sheng, Liang, Yi-Zeng, Deng, Zhe, Hu, Qian-Nan, He, Min, Xu, Qing-Song, Zhou, Guang-Hua, Zhang, Liu-Xia, Deng, Zi-xin, Liu, Shao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618265/
https://www.ncbi.nlm.nih.gov/pubmed/23577055
http://dx.doi.org/10.1371/journal.pone.0057680