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Genome-Scale Screening of Drug-Target Associations Relevant to K(i) Using a Chemogenomics Approach
The identification of interactions between drugs and target proteins plays a key role in genomic drug discovery. In the present study, the quantitative binding affinities of drug-target pairs are differentiated as a measurement to define whether a drug interacts with a protein or not, and then a che...
Autores principales: | Cao, Dong-Sheng, Liang, Yi-Zeng, Deng, Zhe, Hu, Qian-Nan, He, Min, Xu, Qing-Song, Zhou, Guang-Hua, Zhang, Liu-Xia, Deng, Zi-xin, Liu, Shao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618265/ https://www.ncbi.nlm.nih.gov/pubmed/23577055 http://dx.doi.org/10.1371/journal.pone.0057680 |
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