Structurally differentiated cis-elements that interact with PU.1 are functionally distinguishable in acute promyelocytic leukemia

BACKGROUND: Transcription factor PU.1, a member of the ETS family, is a master regulator of myeloid differentiation whose functional disruption is often associated with acute myeloid leukemia (AML). Although much has been learned about PU.1 over the past decades, relatively little is known about cis...

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Detalles Bibliográficos
Autores principales: Qian, Maoxiang, Jin, Wen, Zhu, Xuehua, Jia, Xiaohong, Yang, Xianwen, Du, Yanzhi, Wang, Kankan, Zhang, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618267/
https://www.ncbi.nlm.nih.gov/pubmed/23547873
http://dx.doi.org/10.1186/1756-8722-6-25

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