DIDS (4,4-Diisothiocyanatostilbenedisulphonic Acid) Induces Apoptotic Cell Death in a Hippocampal Neuronal Cell Line and Is Not Neuroprotective against Ischemic Stress

DIDS is a commonly used anion channel antagonist that is putatively cytoprotective against ischemic insult. However, recent reports indicate potentially deleterious secondary effects of DIDS. To assess the impact of DIDS on cellular viability comprehensively we examined neuronal morphology and funct...

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Detalles Bibliográficos
Autores principales: Pamenter, Matthew E., Perkins, Guy A., Gu, Xiang Q., Ellisman, Mark H., Haddad, Gabriel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618322/
https://www.ncbi.nlm.nih.gov/pubmed/23577164
http://dx.doi.org/10.1371/journal.pone.0060804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618322/
https://www.ncbi.nlm.nih.gov/pubmed/23577164
http://dx.doi.org/10.1371/journal.pone.0060804

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