Quantitative Assessment of the Effect of Cytochrome P450 2C9 Gene Polymorphism and Colorectal Cancer

CYP2C9 enzyme activity is involved in the metabolism of substances related to colorectal cancer (CRC), and it is functionally linked to a genetic polymorphism. Two allelic variants of the CYP2C9 gene, namely CYP2C9*2 and CYP2C9*3, differ from wild-type CYP2C9*1 by single amino acid substitutions. Th...

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Detalles Bibliográficos
Autores principales: Zhao, Yuan, Han, Yusong, Zhang, Liang, Wang, Yichao, Ma, Yushui, Zhang, Feng, Fu, Da, Wang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618415/
https://www.ncbi.nlm.nih.gov/pubmed/23577132
http://dx.doi.org/10.1371/journal.pone.0060607

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