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Functional Profiling of Precursor MicroRNAs Identifies MicroRNAs Essential for Glioma Proliferation

Cancer initiation and progression involve microRNAs that can function like tumor suppressors and oncogenes. The functional significance of most miRNAs is currently unknown. To determine systematically which microRNAs are essential for glioma growth, we screened a precursor microRNA library in three...

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Detalles Bibliográficos
Autores principales: Haapa-Paananen, Saija, Chen, Ping, Hellström, Kirsi, Kohonen, Pekka, Hautaniemi, Sampsa, Kallioniemi, Olli, Perälä, Merja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618426/
https://www.ncbi.nlm.nih.gov/pubmed/23577178
http://dx.doi.org/10.1371/journal.pone.0060930