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SCF(Fbxl3) Ubiquitin Ligase Targets Cryptochromes at Their Cofactor Pocket

The flavoprotein cryptochromes (CRYs) act as blue-light receptors in plants and insects, but perform light-independent functions at the core of the mammalian circadian clock. To drive clock oscillations, mammalian CRYs associate with the Period proteins (PERs) and together inhibit the transcription...

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Detalles Bibliográficos
Autores principales: Xing, Weiman, Busino, Luca, Hinds, Thomas R., Marionni, Samuel T., Saifee, Nabiha H., Bush, Matthew F., Pagano, Michele, Zheng, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618506/
https://www.ncbi.nlm.nih.gov/pubmed/23503662
http://dx.doi.org/10.1038/nature11964