Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses

Although susceptibility of neurons in the brain to microbial infection is a major determinant of clinical outcome, little is known about the molecular factors governing this vulnerability. Here we show that two types of neurons from distinct brain regions showed differential permissivity to replicat...

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Detalles Bibliográficos
Autores principales: Cho, Hyelim, Proll, Sean C, Szretter, Kristy J, Katze, Michael G, Gale, Michael, Diamond, Michael S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618596/
https://www.ncbi.nlm.nih.gov/pubmed/23455712
http://dx.doi.org/10.1038/nm.3108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618596/
https://www.ncbi.nlm.nih.gov/pubmed/23455712
http://dx.doi.org/10.1038/nm.3108

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