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Influence of excipients and processing conditions on the development of agglomerates of racecadotril by crystallo-co-agglomeration
PURPOSE: The purpose of the present investigation was to improve the flow and mechanical properties of racecadotril by a crystallo-co-agglomeration (CCA) technique. Direct tableting is a requirement of pharmaceutical industries. Poor mechanical properties of crystalline drug particles require wet gr...
Autores principales: | Garala, Kevin, Patel, Jaydeep, Patel, Anjali, Raval, Mihir, Dharamsi, Abhay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618635/ https://www.ncbi.nlm.nih.gov/pubmed/23580935 http://dx.doi.org/10.4103/2230-973X.106996 |
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