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Development of time controlled chronomodulated tablet with swelling and rupturable layers: Optimization of factors influencing lag-time and drug release

INTRODUCTION: A tablet system consisting of cores coated with two layers of swelling and rupturable coatings was prepared and evaluated as time controlled chronomodulated tablet. MATERIALS AND METHODS: Cores containing Montelukast sodium as model drug were prepared by direct compression and then coa...

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Detalles Bibliográficos
Autores principales: Desai, Mayur, Jivani, Rishad R, Patel, Laxman D, Jivani, Noordin P, Sonagara, Bhavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618637/
https://www.ncbi.nlm.nih.gov/pubmed/23580937
http://dx.doi.org/10.4103/2230-973X.107005