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Development of time controlled chronomodulated tablet with swelling and rupturable layers: Optimization of factors influencing lag-time and drug release
INTRODUCTION: A tablet system consisting of cores coated with two layers of swelling and rupturable coatings was prepared and evaluated as time controlled chronomodulated tablet. MATERIALS AND METHODS: Cores containing Montelukast sodium as model drug were prepared by direct compression and then coa...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618637/ https://www.ncbi.nlm.nih.gov/pubmed/23580937 http://dx.doi.org/10.4103/2230-973X.107005 |