Cargando…
Selective Intermittent Preventive Treatment of Vivax Malaria: Reduction of Malaria Incidence in an Open Cohort Study in Brazilian Amazon
In children, the Intermittent Preventive Treatment (IPTc), currently called Seasonal Malaria Chemoprevention (SMC), was considered effective on malaria control due to the reduction of its incidence in Papua New Guinea and in some areas with seasonal malaria in Africa. However, the IPT has not been i...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618938/ https://www.ncbi.nlm.nih.gov/pubmed/23577276 http://dx.doi.org/10.1155/2013/310246 |
_version_ | 1782265449128394752 |
---|---|
author | Katsuragawa, Tony Hiroshi Gil, Luiz Herman Soares de Lima, Alzemar Alves Freitag, Elci Marlei dos Santos, Tatiana Marcondes do Nascimento Filha, Maria Teixeira dos Santos Júnior, Alcides Procópio Justiniano da Silva, Josiane Mendes Rodrigues, Aline de Freitas Tada, Mauro Shugiro Fontes, Cor Jesus Fernandes Pereira da Silva, Luiz Hildebrando |
author_facet | Katsuragawa, Tony Hiroshi Gil, Luiz Herman Soares de Lima, Alzemar Alves Freitag, Elci Marlei dos Santos, Tatiana Marcondes do Nascimento Filha, Maria Teixeira dos Santos Júnior, Alcides Procópio Justiniano da Silva, Josiane Mendes Rodrigues, Aline de Freitas Tada, Mauro Shugiro Fontes, Cor Jesus Fernandes Pereira da Silva, Luiz Hildebrando |
author_sort | Katsuragawa, Tony Hiroshi |
collection | PubMed |
description | In children, the Intermittent Preventive Treatment (IPTc), currently called Seasonal Malaria Chemoprevention (SMC), was considered effective on malaria control due to the reduction of its incidence in Papua New Guinea and in some areas with seasonal malaria in Africa. However, the IPT has not been indicated because of its association with drug resistance and for hindering natural immunity development. Thus, we evaluated the alternative IPT impact on malaria incidence in three riverside communities on Madeira River, in the municipality of Porto Velho, RO. We denominate this scheme Selective Intermittent Preventive Treatment (SIPT). The SIPT consists in a weekly dose of two 150 mg chloroquine tablets for 12 weeks, for adults, and an equivalent dose for children, after complete supervised treatment for P. vivax infection. This scheme is recommend by Brazilian Health Ministry to avoid frequent relapses. The clinic parasitological and epidemiological surveillance showed a significant reduction on vivax malaria incidence. The results showed a reduction on relapses and recurrence of malaria after SIPT implementation. The SIPT can be effective on vivax malaria control in localities with high transmission risk in the Brazilian Amazon. |
format | Online Article Text |
id | pubmed-3618938 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-36189382013-04-10 Selective Intermittent Preventive Treatment of Vivax Malaria: Reduction of Malaria Incidence in an Open Cohort Study in Brazilian Amazon Katsuragawa, Tony Hiroshi Gil, Luiz Herman Soares de Lima, Alzemar Alves Freitag, Elci Marlei dos Santos, Tatiana Marcondes do Nascimento Filha, Maria Teixeira dos Santos Júnior, Alcides Procópio Justiniano da Silva, Josiane Mendes Rodrigues, Aline de Freitas Tada, Mauro Shugiro Fontes, Cor Jesus Fernandes Pereira da Silva, Luiz Hildebrando Malar Res Treat Research Article In children, the Intermittent Preventive Treatment (IPTc), currently called Seasonal Malaria Chemoprevention (SMC), was considered effective on malaria control due to the reduction of its incidence in Papua New Guinea and in some areas with seasonal malaria in Africa. However, the IPT has not been indicated because of its association with drug resistance and for hindering natural immunity development. Thus, we evaluated the alternative IPT impact on malaria incidence in three riverside communities on Madeira River, in the municipality of Porto Velho, RO. We denominate this scheme Selective Intermittent Preventive Treatment (SIPT). The SIPT consists in a weekly dose of two 150 mg chloroquine tablets for 12 weeks, for adults, and an equivalent dose for children, after complete supervised treatment for P. vivax infection. This scheme is recommend by Brazilian Health Ministry to avoid frequent relapses. The clinic parasitological and epidemiological surveillance showed a significant reduction on vivax malaria incidence. The results showed a reduction on relapses and recurrence of malaria after SIPT implementation. The SIPT can be effective on vivax malaria control in localities with high transmission risk in the Brazilian Amazon. Hindawi Publishing Corporation 2013 2013-03-21 /pmc/articles/PMC3618938/ /pubmed/23577276 http://dx.doi.org/10.1155/2013/310246 Text en Copyright © 2013 Tony Hiroshi Katsuragawa et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Katsuragawa, Tony Hiroshi Gil, Luiz Herman Soares de Lima, Alzemar Alves Freitag, Elci Marlei dos Santos, Tatiana Marcondes do Nascimento Filha, Maria Teixeira dos Santos Júnior, Alcides Procópio Justiniano da Silva, Josiane Mendes Rodrigues, Aline de Freitas Tada, Mauro Shugiro Fontes, Cor Jesus Fernandes Pereira da Silva, Luiz Hildebrando Selective Intermittent Preventive Treatment of Vivax Malaria: Reduction of Malaria Incidence in an Open Cohort Study in Brazilian Amazon |
title | Selective Intermittent Preventive Treatment of Vivax Malaria: Reduction of Malaria Incidence in an Open Cohort Study in Brazilian Amazon |
title_full | Selective Intermittent Preventive Treatment of Vivax Malaria: Reduction of Malaria Incidence in an Open Cohort Study in Brazilian Amazon |
title_fullStr | Selective Intermittent Preventive Treatment of Vivax Malaria: Reduction of Malaria Incidence in an Open Cohort Study in Brazilian Amazon |
title_full_unstemmed | Selective Intermittent Preventive Treatment of Vivax Malaria: Reduction of Malaria Incidence in an Open Cohort Study in Brazilian Amazon |
title_short | Selective Intermittent Preventive Treatment of Vivax Malaria: Reduction of Malaria Incidence in an Open Cohort Study in Brazilian Amazon |
title_sort | selective intermittent preventive treatment of vivax malaria: reduction of malaria incidence in an open cohort study in brazilian amazon |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618938/ https://www.ncbi.nlm.nih.gov/pubmed/23577276 http://dx.doi.org/10.1155/2013/310246 |
work_keys_str_mv | AT katsuragawatonyhiroshi selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon AT gilluizhermansoares selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon AT delimaalzemaralves selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon AT freitagelcimarlei selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon AT dossantostatianamarcondes selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon AT donascimentofilhamariateixeira selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon AT dossantosjunioralcidesprocopiojustiniano selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon AT dasilvajosianemendes selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon AT rodriguesalinedefreitas selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon AT tadamauroshugiro selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon AT fontescorjesusfernandes selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon AT pereiradasilvaluizhildebrando selectiveintermittentpreventivetreatmentofvivaxmalariareductionofmalariaincidenceinanopencohortstudyinbrazilianamazon |