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Powerful vascular protection by combining cilnidipine with valsartan in stroke-prone, spontaneously hypertensive rats
Cilnidipine is an L- and N-type calcium channel blocker (CCB), and amlodipine is an L-type CCB. Valsartan (10 mg kg(−1)), valsartan (10 mg kg(−1)) and amlodipine (1 mg kg(−1)), and valsartan (10 mg kg(−1)) and cilnidipine (1 mg kg(−1)) were administered once daily for 2 weeks to stroke-prone, sponta...
Autores principales: | Takai, Shinji, Jin, Denan, Aritomi, Shizuka, Niinuma, Kazumi, Miyazaki, Mizuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619050/ https://www.ncbi.nlm.nih.gov/pubmed/23190689 http://dx.doi.org/10.1038/hr.2012.187 |
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