Cargando…

miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis

BACKGROUND: Clear cell renal cancer frequently harbours von Hippel–Lindau (VHL) gene mutations, leading to stabilisation of the hypoxia-inducible factors (HIFs) and expression of their target genes. We investigated HIF-1 and HIF-2 in the regulation of microRNA-210 (miR-210), and its clinical relevan...

Descripción completa

Detalles Bibliográficos
Autores principales:	McCormick, R I, Blick, C, Ragoussis, J, Schoedel, J, Mole, D R, Young, A C, Selby, P J, Banks, R E, Harris, A L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619073/ https://www.ncbi.nlm.nih.gov/pubmed/23449350 http://dx.doi.org/10.1038/bjc.2013.56

Ejemplares similares

Identification of a hypoxia-regulated miRNA signature in bladder cancer and a role for miR-145 in hypoxia-dependent apoptosis
por: Blick, C, et al.
Publicado: (2015)

Expression of miR-210 in relation to other measures of hypoxia and prediction of benefit from hypoxia modification in patients with bladder cancer
por: Irlam-Jones, J J, et al.
Publicado: (2016)

MicroRNA-210 Regulates Mitochondrial Free Radical Response to Hypoxia and Krebs Cycle in Cancer Cells by Targeting Iron Sulfur Cluster Protein ISCU
por: Favaro, Elena, et al.
Publicado: (2010)

Serum microRNA-210 as a potential noninvasive biomarker for the diagnosis and prognosis of glioma
por: Lai, N-s, et al.
Publicado: (2015)

Association of serum amyloid A protein and peptide fragments with prognosis in renal cancer
por: Wood, S L, et al.
Publicado: (2010)

Hypoxia-inducible factor-1α and -2α are expressed in most rectal cancers but only hypoxia-inducible factor-1α is associated with prognosis
por: Rasheed, S, et al.
Publicado: (2009)

The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis
por: Gee, H E, et al.
Publicado: (2011)

PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer
por: Wigfield, S M, et al.
Publicado: (2008)

Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia
por: Koukourakis, M I, et al.
Publicado: (2010)

An immunohistochemically positive E-cadherin status is not always predictive for a good prognosis in human breast cancer
por: Querzoli, P, et al.
Publicado: (2010)

Expression of LRIG1 is associated with good prognosis and human papillomavirus status in oropharyngeal cancer
por: Lindquist, D, et al.
Publicado: (2014)

Hypoxia-associated markers in gastric carcinogenesis and HIF-2α in gastric and gastro-oesophageal cancer prognosis
por: Griffiths, E A, et al.
Publicado: (2008)

Prognostic utility of pre-operative circulating osteopontin, carbonic anhydrase IX and CRP in renal cell carcinoma
por: Sim, S H, et al.
Publicado: (2012)

Systematic review and meta-analysis of immunohistochemical prognostic biomarkers in resected oesophageal adenocarcinoma
por: McCormick Matthews, L H, et al.
Publicado: (2015)

Rho-GTPase activating-protein 18: a biomarker associated with good prognosis in invasive breast cancer
por: Aleskandarany, Mohammed A, et al.
Publicado: (2017)

Pre-operative urinary cathepsin D is associated with survival in patients with renal cell carcinoma
por: Vasudev, N S, et al.
Publicado: (2009)

Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer
por: Jubb, A M, et al.
Publicado: (2009)

Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis
por: Zheng, H-C, et al.
Publicado: (2006)

No relationship between thymidine phosphorylase (TP, PD-ECGF) expression and hypoxia in carcinoma of the cervix
por: Kabuubi, P, et al.
Publicado: (2006)

Alternative splicing variant of the hypoxia marker carbonic anhydrase IX expressed independently of hypoxia and tumour phenotype
por: Barathova, M, et al.
Publicado: (2008)

Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer
por: Ord, J J, et al.
Publicado: (2005)

Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression
por: Couvelard, A, et al.
Publicado: (2005)

Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype
por: Ameri, K, et al.
Publicado: (2010)

‘Desperate house genes’: the dramatic example of hypoxia
por: Caradec, J, et al.
Publicado: (2010)

New insights into the pathology of pulmonary hypertension: implication of the miR-210/ISCU1/2/Fe-S axis
por: Tang, Haiyang, et al.
Publicado: (2015)

Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia
por: Maftouh, M, et al.
Publicado: (2014)

Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer
por: Shaw, R J, et al.
Publicado: (2009)

Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production
por: Ullmann, Pit, et al.
Publicado: (2016)

EMAP-II-dependent lymphocyte killing is associated with hypoxia in colorectal cancer
por: Youssef, M M S, et al.
Publicado: (2006)

The influence of invasive growth pattern and microvessel density on prognosis in colorectal cancer and colorectal liver metastases
por: Rajaganeshan, R, et al.
Publicado: (2007)

A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-κB promotes gastric tumour growth and angiogenesis
por: Nam, S Y, et al.
Publicado: (2011)

Expression of carbonic anhydrase 9, a potential intrinsic marker of hypoxia, is associated with poor prognosis in oesophageal squamous cell carcinoma
por: Tanaka, N, et al.
Publicado: (2008)

Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer
por: Angst, E, et al.
Publicado: (2006)

Bicalutamide-induced hypoxia potentiates RUNX2-mediated Bcl-2 expression resulting in apoptosis resistance
por: Browne, G, et al.
Publicado: (2012)

Biomarker-based prognosis in hepatocellular carcinoma: validation and extension of the BALAD model
por: Fox, R, et al.
Publicado: (2014)

Tumour-infiltrating FOXP3(+) lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptor-negative breast cancer
por: West, N R, et al.
Publicado: (2013)

Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer
por: Hussain, S A, et al.
Publicado: (2007)

High expression of TROP2 correlates with poor prognosis in pancreatic cancer
por: Fong, D, et al.
Publicado: (2008)

Increasing expression of hypoxia-inducible proteins in the Barrett's metaplasia–dysplasia–adenocarcinoma sequence
por: Griffiths, E A, et al.
Publicado: (2007)

Mechanisms of local immunosuppression in cutaneous melanoma
por: Polak, M E, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_3v9tc1rgroa0jatj91nfr7ciuv