Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer

BACKGROUND: Evidence for non-steroidal anti-inflammatory drugs (NSAIDs) preventing head and neck cancer (HNC) is inconclusive; however, there is some suggestion that aspirin may exert a protective effect. METHODS: Using data from the United States National Cancer Institute Prostate, Lung, Colorectal...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilson, J C, Murray, L J, Hughes, C M, Black, A, Anderson, L A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619083/
https://www.ncbi.nlm.nih.gov/pubmed/23449358
http://dx.doi.org/10.1038/bjc.2013.73
_version_ 1782265462403366912
author Wilson, J C
Murray, L J
Hughes, C M
Black, A
Anderson, L A
author_facet Wilson, J C
Murray, L J
Hughes, C M
Black, A
Anderson, L A
author_sort Wilson, J C
collection PubMed
description BACKGROUND: Evidence for non-steroidal anti-inflammatory drugs (NSAIDs) preventing head and neck cancer (HNC) is inconclusive; however, there is some suggestion that aspirin may exert a protective effect. METHODS: Using data from the United States National Cancer Institute Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial, we examined the association between aspirin and ibuprofen use and HNC. RESULTS: Regular aspirin use was associated with a significant 22% reduction in HNC risk. No association was observed with regular ibuprofen use. CONCLUSION: Aspirin may have potential as a chemopreventive agent for HNC, but further investigation is warranted.
format Online
Article
Text
id pubmed-3619083
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-36190832014-03-19 Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer Wilson, J C Murray, L J Hughes, C M Black, A Anderson, L A Br J Cancer Short Communication BACKGROUND: Evidence for non-steroidal anti-inflammatory drugs (NSAIDs) preventing head and neck cancer (HNC) is inconclusive; however, there is some suggestion that aspirin may exert a protective effect. METHODS: Using data from the United States National Cancer Institute Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial, we examined the association between aspirin and ibuprofen use and HNC. RESULTS: Regular aspirin use was associated with a significant 22% reduction in HNC risk. No association was observed with regular ibuprofen use. CONCLUSION: Aspirin may have potential as a chemopreventive agent for HNC, but further investigation is warranted. Nature Publishing Group 2013-03-19 2013-02-28 /pmc/articles/PMC3619083/ /pubmed/23449358 http://dx.doi.org/10.1038/bjc.2013.73 Text en Copyright © 2013 Cancer Research UK http://creativecommons.org/licenses/by-nc-sa/3.0/ From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
spellingShingle Short Communication
Wilson, J C
Murray, L J
Hughes, C M
Black, A
Anderson, L A
Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer
title Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer
title_full Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer
title_fullStr Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer
title_full_unstemmed Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer
title_short Non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer
title_sort non-steroidal anti-inflammatory drug and aspirin use and the risk of head and neck cancer
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619083/
https://www.ncbi.nlm.nih.gov/pubmed/23449358
http://dx.doi.org/10.1038/bjc.2013.73
work_keys_str_mv AT wilsonjc nonsteroidalantiinflammatorydrugandaspirinuseandtheriskofheadandneckcancer
AT murraylj nonsteroidalantiinflammatorydrugandaspirinuseandtheriskofheadandneckcancer
AT hughescm nonsteroidalantiinflammatorydrugandaspirinuseandtheriskofheadandneckcancer
AT blacka nonsteroidalantiinflammatorydrugandaspirinuseandtheriskofheadandneckcancer
AT andersonla nonsteroidalantiinflammatorydrugandaspirinuseandtheriskofheadandneckcancer

Ejemplares similares