Rare Though Not Mutually Exclusive: A Report of Three Cases of Concomitant KRAS and BRAF Mutation and a Review of the Literature

KRAS mutations occur frequently in colorectal cancers (CRC) and predict lack of response to anti-epidermal growth factor receptor (EGFR) monoclonal antibody therapy. CRC BRAF mutations, most commonly at V600E, occur less than 10% of the time, and occur usually in KRAS wild-type tumors, and more freq...

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Detalles Bibliográficos
Autores principales: Sahin, Ibrahim Halil, Kazmi, Syed M.A., Yorio, Jeffrey T., Bhadkamkar, Nishin A., Kee, Bryan K., Garrett, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Short Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619093/
https://www.ncbi.nlm.nih.gov/pubmed/23569465
http://dx.doi.org/10.7150/jca.3619

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