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The endoplasmic reticulum stress marker CHOP predicts survival in malignant mesothelioma

BACKGROUND: Mesothelioma is an incurable cancer originating from the mesothelial cells that line the pleural, peritoneal and pericardial cavities. These cells synthesise large quantities of surface glycoproteins, rendering them dependent upon efficient endoplasmic reticulum (ER) function. When faced...

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Detalles Bibliográficos
Autores principales: Dalton, L E, Clarke, H J, Knight, J, Lawson, M H, Wason, J, Lomas, D A, Howat, W J, Rintoul, R C, Rassl, D M, Marciniak, S J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619254/
https://www.ncbi.nlm.nih.gov/pubmed/23412101
http://dx.doi.org/10.1038/bjc.2013.66