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Using macrophage activation to augment immunotherapy of established tumours
BACKGROUND: Successful immunotherapy will require alteration of the tumour microenvironment and/or decreased immune suppression. Tumour-associated macrophages (TAMs) are one major factor affecting tumour microenvironment. We hypothesised that altering TAM phenotype would augment the efficacy of immu...
Autores principales: | Fridlender, Z G, Jassar, A, Mishalian, I, Wang, L-CS, Kapoor, V, Cheng, G, Sun, J, Singhal, S, Levy, L, Albelda, S M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619255/ https://www.ncbi.nlm.nih.gov/pubmed/23481183 http://dx.doi.org/10.1038/bjc.2013.93 |
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