BRCA1 expression and improved survival in ovarian cancer patients treated with intraperitoneal cisplatin and paclitaxel: a Gynecologic Oncology Group Study

BACKGROUND: Breast cancer 1, early onset (BRCA1) is a tumour-suppressor gene associated with familial epithelial ovarian cancer (EOC). Reduced BRCA1 expression is associated with enhanced sensitivity to platinum-based chemotherapy. We sought to examine the prognostic relevance of BRCA1 expression in...

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Detalles Bibliográficos
Autores principales: Lesnock, J L, Darcy, K M, Tian, C, DeLoia, J A, Thrall, M M, Zahn, C, Armstrong, D K, Birrer, M J, Krivak, T C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619264/
https://www.ncbi.nlm.nih.gov/pubmed/23462720
http://dx.doi.org/10.1038/bjc.2013.70

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