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Preventive Agents for Migraine: Focus on the Antiepileptic Drugs

Migraine is among the 10 most disabling disorders worldwide. It is characterized by episodes of moderate or severe headaches with various degree of disability, resulting in a considerable health burden upon the sufferers and their family. The objective of this article is to review the use of prophyl...

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Detalles Bibliográficos
Autores principales: Shahien, R., Beiruti, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619701/
https://www.ncbi.nlm.nih.gov/pubmed/23650466
http://dx.doi.org/10.4137/JCNSD.S9049
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author Shahien, R.
Beiruti, K.
author_facet Shahien, R.
Beiruti, K.
author_sort Shahien, R.
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description Migraine is among the 10 most disabling disorders worldwide. It is characterized by episodes of moderate or severe headaches with various degree of disability, resulting in a considerable health burden upon the sufferers and their family. The objective of this article is to review the use of prophylaxis with antiepileptic drugs. Particular focus is given to their mechanism of action, metabolism, pharmacokinetics, safety profile, efficacy and to provide a summary of the most relevant clinical studies and patient preference.
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spelling pubmed-36197012013-05-06 Preventive Agents for Migraine: Focus on the Antiepileptic Drugs Shahien, R. Beiruti, K. J Cent Nerv Syst Dis Review Migraine is among the 10 most disabling disorders worldwide. It is characterized by episodes of moderate or severe headaches with various degree of disability, resulting in a considerable health burden upon the sufferers and their family. The objective of this article is to review the use of prophylaxis with antiepileptic drugs. Particular focus is given to their mechanism of action, metabolism, pharmacokinetics, safety profile, efficacy and to provide a summary of the most relevant clinical studies and patient preference. Libertas Academica 2012-02-26 /pmc/articles/PMC3619701/ /pubmed/23650466 http://dx.doi.org/10.4137/JCNSD.S9049 Text en © 2012 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited.
spellingShingle Review
Shahien, R.
Beiruti, K.
Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
title Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
title_full Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
title_fullStr Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
title_full_unstemmed Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
title_short Preventive Agents for Migraine: Focus on the Antiepileptic Drugs
title_sort preventive agents for migraine: focus on the antiepileptic drugs
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619701/
https://www.ncbi.nlm.nih.gov/pubmed/23650466
http://dx.doi.org/10.4137/JCNSD.S9049
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