Cargando…
The Hedgehog Receptor Patched1 in T Cells Is Dispensable for Adaptive Immunity in Mice
Hedgehog (Hh) signaling modulates T cell development and function but its exact role remains a matter of debate. To further address this issue we made use of conditional knock-out mice in which the Hh receptor Patched1 (Ptch) is inactivated in the T cell lineage. Thymocyte development was moderately...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620050/ https://www.ncbi.nlm.nih.gov/pubmed/23577186 http://dx.doi.org/10.1371/journal.pone.0061034 |