Hepatitis C Virus Core Protein Down-Regulates p21(Waf1/Cip1) and Inhibits Curcumin-Induced Apoptosis through MicroRNA-345 Targeting in Human Hepatoma Cells

BACKGROUND: Hepatitis C virus (HCV) has been reported to regulate cellular microRNAs. The HCV core protein is considered to be a potential oncoprotein in HCV-related hepatocellular carcinoma, but HCV core-modulated cellular microRNAs are unknown. The HCV core protein regulates p21(Waf1/Cip1) express...

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Detalles Bibliográficos
Autores principales: Shiu, Tzu-Yue, Huang, Shih-Ming, Shih, Yu-Lueng, Chu, Heng-Cheng, Chang, Wei-Kuo, Hsieh, Tsai-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620056/
https://www.ncbi.nlm.nih.gov/pubmed/23577194
http://dx.doi.org/10.1371/journal.pone.0061089

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