Characterization of FUS Mutations in Amyotrophic Lateral Sclerosis Using RNA-Seq

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease resulting in severe muscle weakness and eventual death by respiratory failure. Although little is known about its pathogenesis, mutations in fused in sarcoma/translated in liposarcoma (FUS) are causative for familial ALS. FUS is a mu...

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Detalles Bibliográficos
Autores principales: van Blitterswijk, Marka, Wang, Eric T., Friedman, Brad A., Keagle, Pamela J., Lowe, Patrick, Leclerc, Ashley Lyn, van den Berg, Leonard H., Housman, David E., Veldink, Jan H., Landers, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620060/
https://www.ncbi.nlm.nih.gov/pubmed/23577159
http://dx.doi.org/10.1371/journal.pone.0060788

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